



HydroxyBMD³ Bone, Joint & Cardiovascular Supplement System
HydroxyBMD³ is a revolutionary bone, joint, and cardiovascular supplement system created to help improve bone quality, health, and strength. The customizable and professional-quality system enables you and your doctor to adjust the supplement to your needs.
HydroxyBMD³ AM includes:
- Bonolive®: Is a natural ingredient based on olive polyphenols. This active ingredient is clinically proven to address post-menopausal concerns such as bone loss, joint discomfort, and blood lipids disbalance.
- MicrobiomeX®: MicrobiomeX® is a first-in-class Flavobiotic® that protects the gut barrier and directly leverages the gut microbiome’s potential.
- VitaCholine®: It’s an essential nutrient for our brain, body, and nervous system, promoting memory, mood, muscle control, and many more cellular functions.
- K2VITAL: An active form of Vitamin K2 that regulates calcium in the body by delivering it to the bones.
HydroxyBMD³ PM contains:
- Microcrystalline Hydroxyapatite: MCHA is a compound derived from bovine bone that contains calcium and phosphate in the form of hydroxyapatite.
- Albion Minerals®: Offers the best chelated and specialty mineral solutions for superior quality, absorption, and bioavailability, scientifically validated with over 160 publications.
- Di-Calcium Malate: Contains a concentrated form of calcium.
Your initial order includes refillable glass bottles. Future orders will be shipped without bottles to reduce waste and encourage reuse. NOW SHIPPING!
Pairs well with

HydroxyBMD³ Bone, Joint & Cardiovascular Supplement System
The Supplement System
Taking vitamins in the morning maximizes their response. AM consists of a perfect blend of micronutrients scientifically formulated to kick start your body and support optimal bone, joint, and cardiovascular health. Its exceptional high-quality ingredients are backed by Clinical Studies. Below are some of the unique benefits of these ingredients.
Bonolive®
- BONE HEALTH BENEFITS Bonolive® is clinically proven to improve bone health in postmenopausal women. A randomized, double-blind, placebo-controlled study proved that Bonolive® has significant effects on bone-building cells (osteoblasts) and bone mineral density. In this study, a 32% increase in osteocalcin levels (μg/L) was observed over 12 months. This finding was statistically significant, and it indicated that there was an increase in osteoblast activity (bone formation). Furthermore, DEXA scans showed that women taking Bonolive® displayed protection of bone mineral density at the lumbar spine and a higher gain of bone mineral density at the femoral neck compared to those taking a placebo.
- JOINT FUNCTIONALITY A randomized, double-blind, placebo-controlled trial that was conducted in collaboration with Nestlé health science showed a significant (46%) decrease in knee pain after 6 months based on the KOOS (Knee injury and Osteoarthritis Outcome Score) as well as a significant change in knee discomfort while walking based on a VAS score (high pain group).
- POST-MENOPAUSAL SYMPTOM RELIEF In this consumer study, we investigated the effect of Bonolive® on self-assessed post-menopause symptoms in healthy post- menopausal women. Self-assessed post-menopausal symptoms scores improved significantly after 14 days and after 28 days Bonolive® supplementation compared to baseline.
MicrobiomeX®
- GUT MICROBIOME MODULATION Clinical research has shown that daily consumption of 500mg of MicrobiomeX® beneficially modulates the gut microbiota. The growth of specific bacterial groups, namely Clostridium cluster XIVa is promoted and particularlythe species belonging to the genus Roseburia spp, which are well-known for their butyrate-producing property and many beneficial health effects
- SHORT-CHAIN FATTY ACID After 12 weeks of 500mg MicrobiomeX consumption, a significant increase in the butyrate proportion of the total SCFA was observed. Furthermore, the butyrate over acetate ratio significantly increased in the MicrobiomeX group compared to the placebo group. Butyrate has health-promoting effects such as positively affecting gut barrier function and lowering gut inflammation.
- GUT INFLAMMATION & IMMUNE HEALTH After 12 weeks of daily supplementation with 500mg of MicrobiomeX®, a strong reduction in faecal calprotectin was shown compared to the placebo group. Calprotectin is an important biomarker of gut inflammation, and its reduction suggests a decrease in pathogen load in the gut.
VitaCholine is considered superior to other forms of choline for several reasons:
- Purity and Safety: VitaCholine is produced through a stringent process that ensures its purity and safety. It is free from contaminants and unwanted additives. It is made using only natural L(+) tartaric acid.
- Enhanced Bioavailability: VitaCholine is highly bioavailable, meaning it is easily absorbed and utilized by the body. This ensures that more of the nutrient reaches the cells where it is needed.
- Stability: VitaCholine is stable and maintains its efficacy over time, making it a reliable source of choline.
- Research-Backed: Numerous studies support the efficacy and benefits of VitaCholine, providing a solid scientific basis for its use.
K2VITAL™ is patented, typically 99.7% all-trans K2 MK-7. Identical to the K2 molecule found in nature and fully bioactive. Vitamin K2 all-trans MK-7 is the biologically active form of vitamin K2, a fat-soluble vital vitamin that supports calcium metabolism. Vitamin K2 activates vitamin K-dependent proteins which help move calcium to where it needs to be in the body, supporting bone and heart. It’s responsible for activating Vitamin K-dependent proteins, helping deposit calcium into the bone.
HYDROXYBMD3 PM is designed to work, while you sleep, delivering two types of calcium and minerals to help with bone building recovering during the body’s natural repair cycle.
Albion Minerals are inorganic mineral salts, like phytates and oxalates, prevalent in seeds, grains, and legumes, can bind to minerals like calcium, iron, and zinc, reducing their absorption. This isn’t the case with chelated minerals, making them ideal for vegetarians and vegans and plant-based supplements. Unlike commonplace, inorganic minerals, Albion mineral amino acid chelates emulate nature’s packaging, optimizing absorption for optimal benefits. Albion chelates form robust bonds with ligand molecules, rendering unique nutritional attributes.
CALCIUM Di-Calcium Malate, produced by Albion Minerals, is a compound structured with two moles of calcium attached to one mole of malic acid. It is designed to be better absorbed than calcium carbonate, maintaining elevated serum calcium levels for a longer period. This compound is particularly useful for bone health and supports normal nerve function. Di-Calcium Malate’s buffer capacity leads to significantly less gas creation and acid rebound compared to calcium carbonate. It is not water-soluble but dissolves at more acidic pH levels.
DI-MAGNESIUM MALATE Albion’s magnesium malate has been shown to provide more bioavailable magnesium compared to other forms, making it easier on the gastrointestinal system and potentially offering several health benefits such as improvements in mood, blood sugar control, exercise performance, and chronic pain.
MICROCRYSTALLINE HYDROXYAPATITE Microcrystalline hydroxyapatite (the best sourced from New Zealand) is a calcium compound that contains minerals in their natural ratios, along with residues of matrix, proteins, and glycosaminoglycans (MCHA). It supports bone mineral composition and can potentially reduce the risk of degenerative joint issues.
Other ingredients: Pullulan (100% GMO free tapioca)
Albion Minerals®, VitaCholine®, and K2VITAL™ are registered trademarks of Balchem Corporation or its subsidiaries.
These statements have not been evaluated by the US Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
If you have any questions, you are always welcome to contact us. We'll get back to you as soon as possible, within 24 hours on weekdays.
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Clinically Researched
Juvent’s patented micro-impact technology delivers gentle vibrations that stimulate bone and muscle health. This low-impact therapy has been proven to enhance circulation, improve balance, and support recovery—all without putting stress on your joints.
Blog posts
Everyone thinks of calcium when they’re looking to optimize their bone health. The real key to resilient bones, flexible joints, and overall wellness lies in a strategic blend of nutrients taken at the right time of day. That’s exactly why Juvent formulated HydroxyBMD3™ PM: a nightly supplement designed to support skeletal repair, joint function, and recovery as your body rests and rebuilds overnight. Two of its powerhouse ingredients, microcrystalline hydroxyapatite and Albion Minerals®, set this formula apart from traditional bone health products. Let’s take a closer look at how they work and why HydroxyBMD3™ PM deserves a spot in your evening routine.
Why Lymphatic Drainage May Be Key in Reducing Leg and Ankle Swelling From Edema
Swollen ankles and heavy, aching legs are more than just uncomfortable; they may be signs of a sluggish lymphatic system. Discovering how to support your body’s natural fluid movement might feel mysterious. You may ask, “Can lymphatic drainage help swollen ankles or legs?” For many, consistent lymphatic drainage is essential in managing symptoms of edema, and understanding how it works can help you make smarter choices about your health.
What's in HydroxyBMD3™ AM? The Many Benefits of MicrobiomeX®, VitaCholine®, and K2VITAL™
When it comes to maintaining lifelong wellness, most people focus on diet and exercise, but targeted nutrition can be just as essential. At Juvent, we believe supplements should do more than just fill nutritional gaps; they should actively support your body's systems. That’s why we developed HydroxyBMD3™ AM, the morning component of a powerful daily supplement system built around three clinically studied ingredients: MicrobiomeX®, VitaCholine®, and K2VITAL™.
What's in HydroxyBMD3™ AM? Three Ways Bonolive® Addresses Postmenopausal Concerns
If you’re navigating life after menopause, you already know it’s more than just a hormonal shift; it’s a total body transition. From changes in mood and metabolism to bone loss and cardiovascular risks, postmenopausal symptoms can affect how you feel every day. That’s why Juvent created HydroxyBMD3™ AM, a targeted supplement designed to support bone health, cardiovascular function, and overall wellness, especially during and after menopause. At the heart of the powerful formula is Bonolive®, a clinically studied ingredient derived from olive leaf extract. This standout ingredient addresses key postmenopausal health concerns, and it’s a smart addition to your daily wellness routine.
Cold Showers, Intermittent Fasting, and Micro-Vibrations: Which Stimuli Help Your Body Thrive?
Sometimes, a little challenge is exactly what the body needs to grow stronger. From cold showers to intermittent fasting, intentional physical stressors can trigger your body to adapt in beneficial ways. However, there are also more comfortable ways to stimulate the body, like with micro-vibrations. So, what are the benefits of cold showers, intermittent fasting, and micro-vibration? Let’s explore these three trending methods and uncover how they may help your body thrive.
How Micro-Vibration Therapy May Support Lymphatic Drainage and Reduce Swelling
Swelling, heaviness, and fatigue in your legs, ankles, or arms could be more than just a long day on your feet. They may be signs your lymphatic system isn’t functioning optimally. Fortunately, innovative wellness tools like micro-vibration therapy devices are helping people support their lymphatic flow in a safe and effective way. If you’re exploring how to improve your lymphatic drainage or searching for the best vibration machine for lymphatic drainage, now is the perfect time to learn how the Juvent Micro-Impact Platform® stands apart from other devices on the market, both in safety and science.
Worried About Postmenopausal Memory Loss? Try This
You’re in the middle of a conversation and suddenly forget a word. You walk into a room and can’t remember why. If you’re a woman who has gone through menopause and is experiencing these moments, you’re not alone. Many women experience postmenopausal memory loss and brain fog. While it may be frustrating, these cognitive changes are common, and there are science-backed, natural ways to manage them. With the right habits, tools, and support, you can protect your brain health and feel mentally clearer. Let’s explore more about menopause and why brain fog occurs, as well as what you can do to sharpen your mind.
Which Juvent Micro-Impact Platform Is Right for You?
Would you like to improve bone density, joint comfort, circulation, and overall wellness with a single tool? Juvent’s Micro-Impact Platforms® offer a unique and clinically validated solution to deliver full-body results. Whether you’re looking to use one from home or have one in your clinic to improve patient care, there’s a platform for your needs. The Juvent 1000N, Juvent PRO HD, and Juvent Clinical HD with ASSIST are all top-notch products, but how do you know which one is right for you? We’ve broken down the differences, benefits, and ideal use cases for each of these powerful platforms so you can choose the best fit for your goals.
Five Ways HydroxyBMD³™ Can Improve Bone and Cardiovascular Health
Wellness is a landscape, and there are multiple aspects you can focus on improving, but both bone and cardiovascular health should be priorities. At Juvent, we understand how interconnected your body systems are, which is why we created HydroxyBMD³™, a science-backed supplement designed to support both bone and cardiovascular health in one powerful formula. Improving bone health and protecting your cardiovascular system can be done all at once with HydroxyBMD³ as a comprehensive and convenient solution. Let’s explore five ways HydroxyBMD³ can improve your health, from stronger bones to a more resilient heart.